Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM43445
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists for GPR55
IC50
3304.677±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM43445
Synonyms:
3-[(4Z)-3-methyl-5-oxidanylidene-4-[(Z)-3-phenylprop-2-enylidene]pyrazol-1-yl]benzoic acid | 3-[(4Z)-3-methyl-5-oxo-4-[(Z)-3-phenylprop-2-enylidene]-1-pyrazolyl]benzoic acid | 3-[(4Z)-3-methyl-5-oxo-4-[(Z)-3-phenylprop-2-enylidene]pyrazol-1-yl]benzoic acid | 3-[(4Z)-5-keto-3-methyl-4-[(Z)-3-phenylprop-2-enylidene]-2-pyrazolin-1-yl]benzoic acid | 3-[3-methyl-5-oxo-4-(3-phenyl-2-propen-1-ylidene)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | MLS000690003 | SMR000298721 | cid_5733483
Type:
Small organic molecule
Emp. Form.:
C20H16N2O3
Mol. Mass.:
332.3526
SMILES:
OC(=O)c1cccc(c1)-n1[nH]c(=C)c(=CC=Cc2ccccc2)c1=O |w:14.15|
Structure:
Search PDB for entries with ligand similarity: