Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM47478
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
13130±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM47478
Synonyms:
2-(4-chlorophenyl)sulfonyl-6-methoxy-3-nitro-pyridine | 2-(4-chlorophenyl)sulfonyl-6-methoxy-3-nitropyridine | 2-[(4-chlorophenyl)sulfonyl]-6-methoxy-3-nitropyridine | MLS000851064 | SMR000457307 | cid_2801235
Type:
Small organic molecule
Emp. Form.:
C12H9ClN2O5S
Mol. Mass.:
328.728
SMILES:
COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O
Structure:
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