Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66724
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Human
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66724
Synonyms:
1-(2,4-Dimethyl-phenoxy)-3-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-propan-2-ol | 1-(2,4-dimethylphenoxy)-3-[4-(2-hydroxyethyl)-1-piperazinyl]-2-propanol;hydrochloride | 1-(2,4-dimethylphenoxy)-3-[4-(2-hydroxyethyl)piperazin-1-yl]propan-2-ol;hydrochloride | 1-(2,4-dimethylphenoxy)-3-[4-(2-hydroxyethyl)piperazino]propan-2-ol;hydrochloride | MLS001209715 | SMR000515631 | cid_24746930
Type:
Small organic molecule
Emp. Form.:
C17H28N2O3
Mol. Mass.:
308.4158
SMILES:
Cc1ccc(OCC(O)CN2CCN(CCO)CC2)c(C)c1
Structure:
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