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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78662
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78662
Synonyms:
2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrol[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-(10-phenothiazinyl)ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-ylethanone;chloride | 3-(3,4-Dichloro-phenyl)-1-(2-oxo-2-phenothiazin-10-yl-ethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium | MLS000580307 | SMR000220459 | cid_12005680
Type:
Small organic molecule
Emp. Form.:
C26H20Cl2N3OS
Mol. Mass.:
493.427
SMILES:
Clc1ccc(cc1Cl)-c1c[n+](CC(=O)N2c3ccccc3Sc3ccccc23)c2CCCn12
Structure:
Search PDB for entries with ligand similarity: