Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM67804
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
2730±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM67804
Synonyms:
(4,5-dibromo-6-oxopyridazin-1-yl)methyl 2-chlorobenzoate | 2-chlorobenzoic acid (4,5-dibromo-6-keto-pyridazin-1-yl)methyl ester | 2-chlorobenzoic acid (4,5-dibromo-6-oxo-1-pyridazinyl)methyl ester | MLS000541286 | SMR000126144 | [4,5-bis(bromanyl)-6-oxidanylidene-pyridazin-1-yl]methyl 2-chloranylbenzoate | [4,5-dibromo-6-oxo-1(6H)-pyridazinyl]methyl 2-chlorobenzenecarboxylate | cid_1474487
Type:
Small organic molecule
Emp. Form.:
C12H7Br2ClN2O3
Mol. Mass.:
422.457
SMILES:
Clc1ccccc1C(=O)OCn1ncc(Br)c(Br)c1=O
Structure:
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