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Target
Neurotensin receptor type 1
Ligand
BDBM79546
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
>40000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79546
Synonyms:
MLS000334786 | N-[[3-(1-benzofuran-2-yl)-1-phenyl-pyrazol-4-yl]methylideneamino]pyridine-3-carboxamide | N-[[3-(1-benzofuran-2-yl)-1-phenylpyrazol-4-yl]methylideneamino]pyridine-3-carboxamide | N-[[3-(2-benzofuranyl)-1-phenyl-4-pyrazolyl]methylideneamino]-3-pyridinecarboxamide | N-[[3-(benzofuran-2-yl)-1-phenyl-pyrazol-4-yl]methyleneamino]nicotinamide | SMR000249544 | cid_2449912
Type:
Small organic molecule
Emp. Form.:
C24H17N5O2
Mol. Mass.:
407.4241
SMILES:
O=C(NN=Cc1cn(nc1-c1cc2ccccc2o1)-c1ccccc1)c1cccnc1
Structure:
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