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Target
Bcl-2-related protein A1
Ligand
BDBM79071
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM79071
Synonyms:
4-Amino-isothiazole-3,5-dicarboxylic acid 3-amide 5-((2,3-dihydro-benzo[1,4]dioxin-6-yl)-{[(tetrahydro-furan-2-ylmethyl)-carbamoyl]-p-tolyl-methyl}-amide) | 4-amino-5-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-N-[1-(4-methylphenyl)-2-oxo-2-(oxolan-2-ylmethylamino)ethyl]-1,2-thiazole-3,5-dicarboxamide | 4-amino-N'-(2,3-dihydro-1,4-benzodioxin-6-yl)-N'-[2-keto-1-(p-tolyl)-2-(tetrahydrofurfurylamino)ethyl]isothiazole-3,5-dicarboxamide | 4-amino-N5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N5-[1-(4-methylphenyl)-2-oxo-2-(2-oxolanylmethylamino)ethyl]isothiazole-3,5-dicarboxamide | 4-azanyl-N5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N5-[1-(4-methylphenyl)-2-oxidanylidene-2-(oxolan-2-ylmethylamino)ethyl]-1,2-thiazole-3,5-dicarboxamide | MLS001221856 | SMR000599933 | cid_3180863
Type:
Small organic molecule
Emp. Form.:
C27H29N5O6S
Mol. Mass.:
551.614
SMILES:
Cc1ccc(cc1)C(N(C(=O)c1snc(C(N)=O)c1N)c1ccc2OCCOc2c1)C(=O)NCC1CCCO1
Structure:
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