Reaction Details
Report a problem with these data
Report a problem with these dataTarget
DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM80439
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Temperature
298.15±n/a K
IC50
2330±n/a nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
Inhibitor
Name:
BDBM80439
Synonyms:
1,5-diethyl-2-[2-(1H-indol-3-yl)vinyl]pyridinium | 3-[(E)-2-(1,5-diethyl-2-pyridin-1-iumyl)ethenyl]-1H-indole;iodide | 3-[(E)-2-(1,5-diethylpyridin-1-ium-2-yl)ethenyl]-1H-indole;iodide | 3-[(E)-2-(1,5-diethylpyridin-1-ium-2-yl)vinyl]-1H-indole;iodide | MLS000698168 | SMR000228467 | cid_15945818
Type:
Small organic molecule
Emp. Form.:
C19H21N2
Mol. Mass.:
277.3829
SMILES:
CCc1ccc(\C=C\c2c[nH]c3ccccc23)[n+](CC)c1
Structure:
