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Target
Platelet-activating factor receptor
Ligand
BDBM50002831
Substrate
n/a
Ki
268±n/a nM
Comments
PDSP_1048
Citation
 Tahraoui, L; Floch, A; Cavero, I Functional validation of platelet-activating factor receptor sites characterized biochemically by a specific and reproducible [3H]platelet-activating factor binding in human platelets. J Pharmacol Exp Ther 252:1221-7 (1990) [PubMed] 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM50002831
Synonyms:
(2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan | (2S,5S)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan | (E)-(1R,2R,3R,5R,12S,13R,16S)-16-Hydroxymethyl-5,9,12,13-tetramethyl-4-oxa-tricyclo[10.3.1.0*3,5*]hexadec-8-en-2-ol | (L 652731)2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan | 2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan | 2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652,731) | 2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652731) | CHEMBL297624 | L-652731
Type:
Small organic molecule
Emp. Form.:
C22H28O7
Mol. Mass.:
404.4535
SMILES:
COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1
Structure:
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