Reaction Details
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Report a problem with these dataTarget
Prostacyclin receptor
Ligand
BDBM50213982
Substrate
n/a
Ki
735±n/a nM
Comments
PDSP_5306
Citation
MacDermot, J; Blair, IA; Cresp, TM Prostacyclin receptors of a neuronal hybrid cell line. Divalent citations and ligand-receptor coupling. Biochem Pharmacol 30:2041-4 (1981) [PubMed] Article More Info.:
Target
Name:
Prostacyclin receptor
Synonyms:
PI2R_MOUSE | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Ptgir
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44475.65
Organism:
Mouse
Description:
Prostaglandin I2 PTGIR MOUSE::P43252
Residue:
415
Sequence:
MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
Inhibitor
Name:
BDBM50213982
Synonyms:
(E)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid | PGE2, 5,6-trans
Type:
Small organic molecule
Emp. Form.:
C20H32O5
Mol. Mass.:
352.4651
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C\CCCC(O)=O
Structure:
