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Target
Beta-galactosidase
Ligand
BDBM50243651
Substrate
n/a
Meas. Tech.
ChEMBL_1672826 (CHEMBL4022855)
IC50
5000000±n/a nM
Citation
 D'Alonzo, D; De Fenza, M; Porto, C; Iacono, R; Huebecker, M; Cobucci-Ponzano, B; Priestman, DA; Platt, F; Parenti, G; Moracci, M; Palumbo, G; Guaragna, A N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of?-Glucosidase Activity for the Treatment of Pompe Disease. J Med Chem 60:9462-9469 (2017) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
Acid beta-galactosidase | BGAL_MOUSE | Bgl | Glb-1 | Glb1 | Lactase
Type:
PROTEIN
Mol. Mass.:
73125.63
Organism:
Mouse
Description:
ChEMBL_701784
Residue:
647
Sequence:
MLRVPLCTPLPLLALLQLLGAAHGIYNVTQRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDYDYLRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQDLYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTPYEPQPTSYDYDAPLSEAGDLTKKYFALREVIQMFKEVPEGPIPPSTPKFAYGKVALRKFKTVAEALGILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPFNGVRDRAYVSVDGVPQGILDRNLMTALNIRGKAGATLDILVENMGRVNYGRFINDFKGLISNMTINSTVLTNWTVFPLNTEAMVRNHLWGREASDEGHLDGRSTSNSSDLILPTFYVGNFSIPSGIPDLPQDTFIQFPGWSKGQVWINGFNLGRYWPTMGPQKTLFVPRNILTTSAPNNITVLELEFAPCSEGTPELCTVEFVDTPVIS
  
Inhibitor
Name:
BDBM50243651
Synonyms:
CHEMBL4061367
Type:
Small organic molecule
Emp. Form.:
C10H21NO4
Mol. Mass.:
219.278
SMILES:
CCCCN1C[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1CO |r|
Structure:
Search PDB for entries with ligand similarity: