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Target
Delta-type opioid receptor
Ligand
BDBM50340646
Substrate
n/a
Meas. Tech.
ChEMBL_1734780 (CHEMBL4150316)
Ki
>100000±n/a nM
Citation
 De Marco, R; Bedini, A; Spampinato, S; Comellini, L; Zhao, J; Artali, R; Gentilucci, L Constraining Endomorphin-1 by ?,?-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel ?-Opioid Receptor Selective Partial Agonist. J Med Chem 61:5751-5757 (2018) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50340646
Synonyms:
CHEMBL4159127
Type:
Small organic molecule
Emp. Form.:
C33H34N6O7
Mol. Mass.:
626.6591
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)NC[C@@H]1OC(=O)N([C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O |r|
Structure:
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