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Target
Mu-type opioid receptor
Ligand
BDBM50340646
Substrate
n/a
Meas. Tech.
ChEMBL_1734779 (CHEMBL4150315)
Ki
>100000±n/a nM
Citation
 De Marco, R; Bedini, A; Spampinato, S; Comellini, L; Zhao, J; Artali, R; Gentilucci, L Constraining Endomorphin-1 by ?,?-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel ?-Opioid Receptor Selective Partial Agonist. J Med Chem 61:5751-5757 (2018) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50340646
Synonyms:
CHEMBL4159127
Type:
Small organic molecule
Emp. Form.:
C33H34N6O7
Mol. Mass.:
626.6591
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)NC[C@@H]1OC(=O)N([C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O |r|
Structure:
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