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Target
Thromboxane A2 receptor
Ligand
BDBM50279755
Substrate
n/a
Meas. Tech.
ChEMBL_209431 (CHEMBL814288)
IC50
7.4±n/a nM
Citation
 Shiraishi, M; Kato, K; Terao, S; Ashida, Y; Terashita, Z; Kito, G Quinones. 4. Novel eicosanoid antagonists: synthesis and pharmacological evaluation. J Med Chem 32:2214-21 (1989) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50279755
Synonyms:
7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid | CHEMBL70972 | Seratrodast
Type:
Small organic molecule
Emp. Form.:
C22H26O4
Mol. Mass.:
354.4394
SMILES:
Cc1c(C)c(O)c(C(=CCCCCC(O)=O)c2ccccc2)c(C)c1O |w:8.8|
Structure:
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