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Target
Galectin-3
Ligand
BDBM50451464
Substrate
n/a
Meas. Tech.
ChEMBL_1745494 (CHEMBL4180004)
EC50
67700±n/a nM
Citation
 Marchiori, MF; Riul, TB; Oliveira Bortot, L; Andrade, P; Junqueira, GG; Foca, G; Doti, N; Ruvo, M; Dias-Baruffi, M; Carvalho, I; Campo, VL Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion. Bioorg Med Chem 25:6049-6059 (2017) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Human
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM50451464
Synonyms:
CHEMBL4211695
Type:
Small organic molecule
Emp. Form.:
C22H28N6O8S
Mol. Mass.:
536.558
SMILES:
CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](OCc2cn(nn2)-c2ccc(cc2)S(=O)(=O)Nc2nc(C)cc(C)n2)[C@H]1O |r|
Structure:
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