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Target
Prostaglandin E synthase
Ligand
BDBM50453468
Substrate
n/a
Meas. Tech.
ChEMBL_1750196 (CHEMBL4184956)
IC50
12000±n/a nM
Citation
  TBA Bioorg Med Chem Lett 28:334-338 (2018) [PubMed]  Article 
Target
Name:
Prostaglandin E synthase
Synonyms:
5.3.99.3 | Microsomal prostaglandin E synthase 1 | PTGES_MOUSE | Pges | Prostaglandin E synthase | Ptges | mPGES-1
Type:
PROTEIN
Mol. Mass.:
17293.88
Organism:
Mus musculus
Description:
ChEMBL_104562
Residue:
153
Sequence:
MPSPGLVMESGQVLPAFLLCSTLLVIKMYAVAVITGQMRLRKKAFANPEDALKRGGLQYYRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPLIAWIHFLVVLTGRVVHTVAYLGKLNPRLRSGAYVLAQFSCFSMALQILWEVAHHL
  
Inhibitor
Name:
BDBM50453468
Synonyms:
CHEMBL4205849
Type:
Small organic molecule
Emp. Form.:
C18H20O2
Mol. Mass.:
268.3502
SMILES:
COc1ccc(C\C=C\Cc2ccc(OC)cc2)cc1
Structure:
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