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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM21753
Substrate
n/a
Meas. Tech.
ChEMBL_1797043 (CHEMBL4269160)
EC50
170±n/a nM
Citation
 Li, Z; Zhou, Z; Deng, F; Li, Y; Zhang, D; Zhang, L Design, synthesis, and biological evaluation of novel pan agonists of FFA1, PPAR? and PPAR?. Eur J Med Chem 159:267-276 (2018) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM21753
Synonyms:
2-[(1S)-5-(3-phenoxypropoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid | Indanylacetic Acid Analog, 17a
Type:
Small organic molecule
Emp. Form.:
C20H22O4
Mol. Mass.:
326.3863
SMILES:
OC(=O)C[C@@H]1CCc2cc(OCCCOc3ccccc3)ccc12 |r|
Structure:
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