Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50467928
Substrate
n/a
Meas. Tech.
ChEMBL_1797351 (CHEMBL4269468)
Ki
350±n/a nM
Citation
 Gadhiya, S; Cordone, P; Pal, RK; Gallicchio, E; Wickstrom, L; Kurtzman, T; Ramsey, S; Harding, WW New Dopamine D3-Selective Receptor Ligands Containing a 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Motif. ACS Med Chem Lett 9:990-995 (2018) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50467928
Synonyms:
CHEMBL4291172
Type:
Small organic molecule
Emp. Form.:
C21H25BrN2O3
Mol. Mass.:
433.339
SMILES:
COc1cc2CCN(CCCCNC(=O)c3ccc(Br)cc3)Cc2cc1O
Structure:
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