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Target
Melatonin receptor type 1C
Ligand
BDBM50476612
Substrate
n/a
Meas. Tech.
ChEMBL_444320 (CHEMBL893556)
EC50
3.3±n/a nM
Citation
 Faust, R; Garratt, PJ; Trujillo Pérez, MA; Piccio, VJ; Madsen, C; Stenstrĝm, A; Frĝlund, B; Davidson, K; Teh, MT; Sugden, D 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorg Med Chem 15:4543-51 (2007) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
MTR1C_XENLA | Melatonin 1C | Melatonin receptor 1C | Melatonin receptor type 1C | mtnr1c
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47442.40
Organism:
African clawed frog
Description:
Melatonin 1C 0 Xenopus::P49219
Residue:
420
Sequence:
MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
  
Inhibitor
Name:
BDBM50476612
Synonyms:
CHEMBL233728
Type:
Small organic molecule
Emp. Form.:
C13H15BrN2O2
Mol. Mass.:
311.174
SMILES:
COc1cc(Br)c2[nH]cc(CCNC(C)=O)c2c1
Structure:
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