Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50482325
Substrate
n/a
Meas. Tech.
ChEMBL_639626 (CHEMBL1175304)
Kd
1490±n/a nM
Citation
 Eleftheratos, S; Spearpoint, P; Ortore, G; Kolocouris, A; Martinelli, A; Martin, S; Hay, A Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model. Bioorg Med Chem Lett 20:4182-7 (2010) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I000F | Matrix protein 2 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11173.62
Organism:
Influenza A virus
Description:
ChEMBL_117202
Residue:
97
Sequence:
MSLLTEVETPTRNGWECSCSDSSDPLVIAASIIGILHFILWILDRLFFKCIYRRLKYGLKRGPSTEGVPKSMREEYRQEQQNAVDVDDGHFVNIELE
  
Inhibitor
Name:
BDBM50482325
Synonyms:
CHEMBL1172240
Type:
Small organic molecule
Emp. Form.:
C13H19NO
Mol. Mass.:
205.2961
SMILES:
O=C1CCC2(N1)C1CC3CC(C1)CC2C3 |TLB:5:4:10.11.12:8.7.14,14:13:9.8.7:11,THB:3:4:10.11.12:8.7.14,5:4:9.8.7:11,9:8:4:10.11.12,9:10:4:8.7.14,14:8:11:4.12.13,(15.75,-16.26,;14.21,-16.34,;13.24,-15.14,;11.8,-15.69,;11.88,-17.23,;13.36,-17.64,;11.87,-18.76,;10.47,-19.11,;9.15,-18.62,;7.95,-19.89,;9.44,-19.47,;10.85,-20.04,;9.44,-17.88,;10.48,-16.65,;9.13,-17.13,)|
Structure:
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