Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50482330
Substrate
n/a
Meas. Tech.
ChEMBL_639626 (CHEMBL1175304)
Kd
2930±n/a nM
Citation
 Eleftheratos, S; Spearpoint, P; Ortore, G; Kolocouris, A; Martinelli, A; Martin, S; Hay, A Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model. Bioorg Med Chem Lett 20:4182-7 (2010) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I000F | Matrix protein 2 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11173.62
Organism:
Influenza A virus
Description:
ChEMBL_117202
Residue:
97
Sequence:
MSLLTEVETPTRNGWECSCSDSSDPLVIAASIIGILHFILWILDRLFFKCIYRRLKYGLKRGPSTEGVPKSMREEYRQEQQNAVDVDDGHFVNIELE
  
Inhibitor
Name:
BDBM50482330
Synonyms:
CHEMBL45505
Type:
Small organic molecule
Emp. Form.:
C14H23N
Mol. Mass.:
205.3391
SMILES:
CN1CCCC11C2CC3CC(C2)CC1C3 |TLB:7:8:12:5.6.11,4:5:10.12.11:8.7.14,4:5:12:8.14.9,THB:1:5:10.12.11:8.7.14,7:6:12:8.14.9,9:10:5:8.7.14,9:8:5:10.12.11,(3.4,-3.45,;3.42,-1.91,;4.58,-.9,;3.99,.53,;2.46,.41,;2.11,-1.09,;2.09,-2.63,;1.08,-3.91,;-.33,-3.33,;-1.84,-3.76,;-.63,-2.48,;.69,-2.98,;-.65,-.99,;.71,-.52,;-.34,-1.74,)|
Structure:
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