Reaction Details Report a problem with these data
Target
Killer cell lectin-like receptor subfamily B member 1A
Ligand
BDBM50482397
Substrate
n/a
Meas. Tech.
ChEMBL_643486 (CHEMBL1212350)
IC50
200±n/a nM
Citation
 Catelani, G; D'Andrea, F; Griselli, A; Guazzelli, L; Nemcová, P; Bezouska, K; Krenek, K; Kren, V Deoxynojirimycin and its hexosaminyl derivatives bind to natural killer cell receptors rNKR-P1A and hCD69. Bioorg Med Chem Lett 20:4645-8 (2010) [PubMed]  Article 
Target
Name:
Killer cell lectin-like receptor subfamily B member 1A
Synonyms:
Antigen 3.2.3 | CD161 antigen-like family member A | CD_antigen=CD161a | KLRBA_RAT | Killer cell lectin-like receptor subfamily B member 1A | Klrb1a | NKR-P1 3.2.3 | NKR-P1A | Natural killer cell surface protein P1-3.2.3 | Nkrp1a
Type:
PROTEIN
Mol. Mass.:
24555.68
Organism:
Rattus norvegicus
Description:
ChEMBL_109233
Residue:
223
Sequence:
MDTARVYLSLKPSKTAAGAQCVSPPSLPPDACRCPRSHRLALKLSCAGLILLVLALVGMSILVRVLVQKPSVEPCRVLIQENLSKTGSPAKLKCPKDWLSHRDKCFHVSQTSITWKESLADCGGKGATLLLVQDQEELRFLRNLTKRISSSFWIGLSYTLSDENWKWINGSTLNSDVLSITGDTEKDSCASVSQDKVLSESCDSDNIWVCQKELKCECMCNDS
  
Inhibitor
Name:
BDBM50482397
Synonyms:
CHEBI:41112 | N-ACETYLMANNOSAMINE
Type:
Small organic molecule
Emp. Form.:
C8H15NO6
Mol. Mass.:
221.2078
SMILES:
CC(=O)N[C@@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O |r|
Structure:
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