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Target
Protease
Ligand
BDBM50483604
Substrate
n/a
Meas. Tech.
ChEMBL_740706 (CHEMBL1763768)
IC50
25±n/a nM
Citation
 Nguyen, JT; Kato, K; Hidaka, K; Kumada, HO; Kimura, T; Kiso, Y Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles. Bioorg Med Chem Lett 21:2425-9 (2011) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
Protease | prt
Type:
PROTEIN
Mol. Mass.:
13462.60
Organism:
Human T-cell leukemia virus type I
Description:
ChEMBL_118454
Residue:
125
Sequence:
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKGPPVIL
  
Inhibitor
Name:
BDBM50483604
Synonyms:
CHEMBL1761463 | KNI-10857
Type:
Small organic molecule
Emp. Form.:
C39H58N6O6S
Mol. Mass.:
738.979
SMILES:
CC(C)(C)CNC(=O)[C@H]1N(CSC1(C)C)C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCCN)c1ccccc1)C(C)(C)C |r|
Structure:
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