Reaction Details Report a problem with these data
Target
4-aminobutyrate aminotransferase, mitochondrial
Ligand
BDBM50488118
Substrate
n/a
Meas. Tech.
ChEMBL_922510 (CHEMBL3076582)
IC50
4960±n/a nM
Citation
  TBA Med Chem Res 22:134-146 (2013)    Article 
Target
Name:
4-aminobutyrate aminotransferase, mitochondrial
Synonyms:
Abat | GABT_RAT | Gabat | Gamma-amino-N-butyrate transaminase
Type:
PROTEIN
Mol. Mass.:
56465.74
Organism:
Rattus norvegicus
Description:
ChEMBL_884621
Residue:
500
Sequence:
MAFLLTTRRLVCSSQKNLHLFTPGSRYISQAAAKVDFEFDYDGPLMKTEVPGPRSQELMKQLNTIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYNHPALAKLVQQPQNASTFINRPALGILPPENFVDKLRESLMSVAPKGMCQLITMACGSCSNENAFKTIFMWYRSKERGQRGFSKEELETCMVNQSPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVTDNQQEEARCLEEVEDLIVKYRKKKRTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMSFSKKMMTGGFFHKEEFRPSAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNVAHAGKTLLTGLLDLQAQYPQFVSRVRGRGTFCSFDTPDEAIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSGILADFK
  
Inhibitor
Name:
BDBM50488118
Synonyms:
CHEMBL2283227
Type:
Small organic molecule
Emp. Form.:
C21H13NO3
Mol. Mass.:
327.3328
SMILES:
[#8]-[#6](=O)-c1cccc(c1)\[#7]=[#6]-1/c2ccccc2-[#6](=O)-c2ccccc-12
Structure:
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