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Target
G2/mitotic-specific cyclin-B
Ligand
BDBM50488812
Substrate
n/a
Meas. Tech.
ChEMBL_932134 (CHEMBL3072206)
IC50
300±n/a nM
Citation
  TBA Med Chem Res 22:3247-3258 (2013)    Article 
Target
Name:
G2/mitotic-specific cyclin-B
Synonyms:
CCNB_PATPE | G2/mitotic-specific cyclin-B
Type:
PROTEIN
Mol. Mass.:
44899.25
Organism:
Asterina pectinifera
Description:
ChEMBL_106612
Residue:
392
Sequence:
MQTACSGNLCGYQLMFSLSTVVTVCRSLRSRNRHWFLKLLGVRLTIAMRCALENISNVAKNNVQAAAKKEIKQKRGMTKSKATSSLQSVIGLHVEPVEKVQSPEPMDMSEVSNALEAFSQNILEMGVDDIDKDDHENPQLCSEYVNDIYLYMRHLEREFKVRTDYMAMQEITERMRTILIDWLVQVHLRFHLLQETLFLTIQILDRYLEGASVSKTKLQLVGVTSMLIAAYEEMYAEIGDFVYITDNAYSKAQIRAMECNILRKLDFNLGKPLCIHFLRRCSKAGGVDGHKHTLSKYIMELTLEYSFVKYDEIAAAALLSTRFWDEDMEWTKSLVHYSAYSEGHLGPIVQKMAVLSQQSHPSPNSRLDQEEDMASSKFMSDQQATQELKSIR
  
Inhibitor
Name:
BDBM50488812
Synonyms:
CHEMBL2295960
Type:
Small organic molecule
Emp. Form.:
C22H26N8O
Mol. Mass.:
418.4948
SMILES:
CCC[C@@H](O)Nc1nc(Nc2cccc(c2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r|
Structure:
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