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Target
P2X purinoceptor 3
Ligand
BDBM50064801
Substrate
n/a
Meas. Tech.
ChEMBL_162330 (CHEMBL766585)
IC50
58300±n/a nM
Citation
 Jacobson, KA; Kim, YC; Wildman, SS; Mohanram, A; Harden, TK; Boyer, JL; King, BF; Burnstock, G A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors. J Med Chem 41:2201-6 (1998) [PubMed]  Article 
Target
Name:
P2X purinoceptor 3
Synonyms:
ATP receptor | P2RX3_RAT | P2X purinoceptor 3 | P2X3 | P2rx3 | Purinergic receptor | ratp2x3 | ratp2x3 + rsa
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44397.63
Organism:
RAT
Description:
Purinergic, P2X3 0 RAT::P49654
Residue:
397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDSQCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEEVTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
  
Inhibitor
Name:
BDBM50064801
Synonyms:
2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda*5*-phospha-benzocyclohepten-1-ylazo)-benzene-1,4-disulfonic acid | CHEMBL304765
Type:
Small organic molecule
Emp. Form.:
C14H14N3O11PS2
Mol. Mass.:
495.378
SMILES:
Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c2COP(O)(=O)OCc2c1O |w:4.3|
Structure:
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