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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50084797
Substrate
n/a
Meas. Tech.
ChEMBL_52222 (CHEMBL663972)
Ki
3.8±n/a nM
Citation
 Palomer, A; Pascual, J; Cabré, F; García, ML; Mauleón, D Derivation of pharmacophore and CoMFA models for leukotriene D(4) receptor antagonists of the quinolinyl(bridged)aryl series. J Med Chem 43:392-400 (2000) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50084797
Synonyms:
4-(2-methyl-1-(7-(quinolin-2-ylmethoxy)naphthalene-2-sulfonamido)propan-2-yl)benzoic acid | 4-{1,1-Dimethyl-2-[7-(quinolin-2-ylmethoxy)-naphthalene-2-sulfonylamino]-ethyl}-benzoic acid | CHEMBL128641
Type:
Small organic molecule
Emp. Form.:
C31H28N2O5S
Mol. Mass.:
540.629
SMILES:
CC(C)(CNS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccc(cc1)C(O)=O
Structure:
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