Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50086160
Substrate
n/a
Meas. Tech.
ChEMBL_29119 (CHEMBL642253)
Ki
309±n/a nM
Citation
 Colotta, V; Catarzi, D; Varano, F; Cecchi, L; Filacchioni, G; Martini, C; Trincavelli, L; Lucacchini, A 1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists. J Med Chem 43:1158-64 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50086160
Synonyms:
5-Methyl-2-phenyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione | CHEMBL16510
Type:
Small organic molecule
Emp. Form.:
C16H12N4O2
Mol. Mass.:
292.2921
SMILES:
Cn1c2ccccc2n2c(nn(-c3ccccc3)c2=O)c1=O
Structure:
Search PDB for entries with ligand similarity: