Reaction Details Report a problem with these data
Target
Galectin-2
Ligand
BDBM50533580
Substrate
n/a
Meas. Tech.
ChEMBL_1925939 (CHEMBL4429011)
Kd
6900±n/a nM
Citation
 Rajput, VK; MacKinnon, A; Mandal, S; Collins, P; Blanchard, H; Leffler, H; Sethi, T; Schambye, H; Mukhopadhyay, B; Nilsson, UJ A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model. J Med Chem 59:8141-7 (2016) [PubMed]  Article 
Target
Name:
Galectin-2
Synonyms:
LEG2_HUMAN | LGALS2
Type:
PROTEIN
Mol. Mass.:
14643.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_491862
Residue:
132
Sequence:
MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
  
Inhibitor
Name:
BDBM50533580
Synonyms:
CHEMBL4446622
Type:
Small organic molecule
Emp. Form.:
C32H34O14S
Mol. Mass.:
674.669
SMILES:
[H][C@]1(O[C@H](CO)[C@H](O)[C@H](OCc2cc3ccccc3oc2=O)[C@H]1O)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](OCc2cc3ccccc3oc2=O)[C@H]1O |r|
Structure:
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