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Target
Melanocortin receptor 3
Ligand
BDBM50549824
Substrate
n/a
Meas. Tech.
ChEMBL_2025872 (CHEMBL4679685)
EC50
66±n/a nM
Citation
 Ericson, MD; Shaikh, R; Larson, CM; Freeman, KT; Haskell-Luevano, C Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist. ACS Med Chem Lett 12:115-120 (2021) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R_MOUSE | Mc3r
Type:
PROTEIN
Mol. Mass.:
35808.24
Organism:
Mus musculus
Description:
ChEMBL_1498848
Residue:
323
Sequence:
MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFIIYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNSMNLG
  
Inhibitor
Name:
BDBM50549824
Synonyms:
CHEMBL4792291
Type:
Small organic molecule
Emp. Form.:
C38H47N9O6
Mol. Mass.:
725.8365
SMILES:
CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O |r|
Structure:
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