Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50550830
Substrate
n/a
Meas. Tech.
ChEMBL_2028573 (CHEMBL4682731)
Ki
>100±n/a nM
Citation
 Abdelrahman, A; Yerande, SG; Namasivayam, V; Klapschinski, TA; Alnouri, MW; El-Tayeb, A; Müller, CE Substituted 4-phenylthiazoles: Development of potent and selective A Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_RAT | Adenosine receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36378.84
Organism:
Rattus norvegicus
Description:
ChEMBL_32934
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
  
Inhibitor
Name:
BDBM50550830
Synonyms:
CHEMBL4787673
Type:
Small organic molecule
Emp. Form.:
C31H22N4O2S
Mol. Mass.:
514.597
SMILES:
Cc1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1
Structure:
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