Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50111167
Substrate
n/a
Meas. Tech.
ChEBML_106361
Ki
5400±n/a nM
Citation
 Mutulis, F; Mutule, I; Lapins, M; Wikberg, JE Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors. Bioorg Med Chem Lett 12:1035-8 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50111167
Synonyms:
2-Amino-5-guanidino-pentanoic acid naphthalen-1-ylmethyl-naphthalen-2-ylmethyl-amide | 2-Amino-5-guanidino-pentanoic acid naphthalen-2-ylmethyl-naphthalen-1-ylmethyl-amide | CHEMBL267020
Type:
Small organic molecule
Emp. Form.:
C28H31N5O
Mol. Mass.:
453.5786
SMILES:
N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Structure:
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