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Target
Melatonin receptor type 1B
Ligand
BDBM50112208
Substrate
n/a
Meas. Tech.
ChEMBL_105404 (CHEMBL710823)
Ki
39±n/a nM
Citation
 Leclerc, V; Yous, S; Delagrange, P; Boutin, JA; Renard, P; Lesieur, D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50112208
Synonyms:
CHEMBL300728 | N-(2-(2-iodo-5-methoxy-1-methyl-4-nitro-1H-indol-3-yl)ethyl)acetamide | N-[2-(2-Iodo-5-methoxy-1-methyl-4-nitro-1H-indol-3-yl)-ethyl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C14H16IN3O4
Mol. Mass.:
417.199
SMILES:
COc1ccc2n(C)c(I)c(CCNC(C)=O)c2c1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: