Reaction Details Report a problem with these data
Target
Stromal cell-derived factor 1
Ligand
BDBM50572262
Substrate
n/a
Meas. Tech.
ChEMBL_2116663 (CHEMBL4825604)
Kd
357000±n/a nM
Citation
 Sprague, DJ; Getschman, AE; Fenske, TG; Volkman, BF; Smith, BC Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12. ACS Med Chem Lett 12:1773-1782 (2021) [PubMed]  Article 
Target
Name:
Stromal cell-derived factor 1
Synonyms:
CXCL12 | Chemokine CXCL12 | SDF1 | SDF1A | SDF1B | SDF1_HUMAN
Type:
Enzyme
Mol. Mass.:
10677.83
Organism:
Homo sapiens (Human)
Description:
P48061
Residue:
93
Sequence:
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
  
Inhibitor
Name:
BDBM50572262
Synonyms:
CHEMBL4879153
Type:
Small organic molecule
Emp. Form.:
C14H13N3O5S2
Mol. Mass.:
367.4
SMILES:
COc1ccc(cc1)-c1nc(SCC(O)=O)nc(SCC(O)=O)n1
Structure:
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