Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM50574782
Substrate
n/a
Meas. Tech.
ChEMBL_2123341 (CHEMBL4832574)
IC50
1950±n/a nM
Citation
 He, YL; Chen, MT; Wang, T; Zhang, MM; Li, YX; Wang, HY; Ding, N Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus. Eur J Med Chem 224:0 (2021) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Human
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50574782
Synonyms:
CHEMBL4866912
Type:
Small organic molecule
Emp. Form.:
C20H17ClN4O2
Mol. Mass.:
380.828
SMILES:
Cc1c(Cl)cccc1OCc1[nH]c2nc(nn2c(=O)c1C)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: