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Target
Lymphocyte antigen 96
Ligand
BDBM50587261
Substrate
n/a
Meas. Tech.
ChEMBL_2171844 (CHEMBL5056978)
Kd
3200±n/a nM
Citation
 Poh Yen, K; Stanslas, J; Zhang, T; Li, H; Wang, X; Kok Meng, C; Kok Wai, L Synthesis of small molecules targeting paclitaxel-induced MyD88 expression in triple-negative breast cancer cell lines. Bioorg Med Chem 49:0 (2021) [PubMed]  Article 
Target
Name:
Lymphocyte antigen 96
Synonyms:
ESOP-1 | ESOP1 | ESOP1 | LY96 | LY96_HUMAN | Ly-96 | Lymphocyte antigen 96 | MD2 | Protein MD-2 | TLR4-MD2
Type:
PROTEIN
Mol. Mass.:
18551.39
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107939
Residue:
160
Sequence:
MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN
  
Inhibitor
Name:
BDBM50587261
Synonyms:
CHEMBL5075055
Type:
Small organic molecule
Emp. Form.:
C21H17F3O2
Mol. Mass.:
358.3537
SMILES:
OC1=C(CCC\C1=C/c1ccc(cc1)C(F)(F)F)C(=O)c1ccccc1 |t:1|
Structure:
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