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Target
Dual specificity protein kinase CLK1
Ligand
BDBM50026622
Substrate
n/a
Meas. Tech.
ChEMBL_2209416 (CHEMBL5122365)
IC50
20±n/a nM
Citation
 Singh, H; Agrawal, DK Recent advances in the development of active hybrid molecules in the treatment of cardiovascular diseases. Bioorg Med Chem 62:0 (2022) [PubMed] 
Target
Name:
Dual specificity protein kinase CLK1
Synonyms:
CDC-like kinase 1 | CDC-like kinase 1 (CLK1) | CDC2-like kinase 1 (CLK1) | CLK | CLK1 | CLK1_HUMAN | Dual specificity protein kinase CLK1 | Dual specificity protein kinase CLK1/CLK4 | Dual specificty protein kinase CLK1
Type:
Protein
Mol. Mass.:
57322.21
Organism:
Homo sapiens (Human)
Description:
P49759
Residue:
484
Sequence:
MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSI
  
Inhibitor
Name:
BDBM50026622
Synonyms:
CHEMBL408982
Type:
Small organic molecule
Emp. Form.:
C13H15NO2S
Mol. Mass.:
249.329
SMILES:
CCN1\C(Sc2ccc(OC)cc12)=C\C(C)=O
Structure:
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