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Target
Hemoglobin HbA
Ligand
BDBM50595164
Substrate
n/a
Meas. Tech.
ChEMBL_2215709 (CHEMBL5128841)
IC50
1060000±n/a nM
Citation
 Oulous, A; Daoudi, NE; Harit, T; Cherfi, M; Bnouham, M; Malek, F New pyrazole-tetrazole hybrid compounds as potent ?-amylase and non-enzymatic glycation inhibitors. Bioorg Med Chem Lett 69:0 (2022) [PubMed] 
Target
Name:
Hemoglobin HbA
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of ChEMBL is 2215709
Components:
This complex has 2 components.
Component 1
Name:
Hemoglobin subunit alpha
Synonyms:
Alpha-globin | HBA1 | HBA2 | HBA_HUMAN | Hemoglobin alpha chain | Hemopressin
Type:
PROTEIN
Mol. Mass.:
15264.42
Organism:
Homo sapiens
Description:
ChEMBL_104753
Residue:
142
Sequence:
MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
  
Component 2
Name:
Hemoglobin subunit beta
Synonyms:
Beta-globin | HBB | HBB_HUMAN | Hemoglobin beta chain | LVV-hemorphin-7 | Spinorphin
Type:
PROTEIN
Mol. Mass.:
16001.74
Organism:
Homo sapiens
Description:
ChEMBL_104753
Residue:
147
Sequence:
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
  
Inhibitor
Name:
BDBM50595164
Synonyms:
CHEMBL5199982
Type:
Small organic molecule
Emp. Form.:
C13H14N6
Mol. Mass.:
254.2905
SMILES:
Cc1cc(Cn2nnc(Cc3ccccc3)n2)n[nH]1
Structure:
Search PDB for entries with ligand similarity: