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Target
Somatostatin receptor type 3
Ligand
BDBM523764
Substrate
n/a
Meas. Tech.
ChEMBL_2223694 (CHEMBL5137207)
Ki
>10000±n/a nM
Citation
 Neumann, WL; Sandoval, KE; Mobayen, S; Minaeian, M; Kukielski, SG; Srabony, KN; Frare, R; Slater, O; Farr, SA; Niehoff, ML; Hospital, A; Kontoyianni, M; Crider, AM; Witt, KA Synthesis and structure-activity relationships of 3,4,5-trisubstituted-1,2,4-triazoles: high affinity and selective somatostatin receptor-4 agonists for Alzheimer's disease treatment. RSC Med Chem 12:1352-1365 (2021) [PubMed] 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM523764
Synonyms:
US11136312, Compound SK-I-55
Type:
Small organic molecule
Emp. Form.:
C25H25FN6O
Mol. Mass.:
444.504
SMILES:
COc1ccc2[nH]cc(Cc3nnc(Cc4ccc(F)cc4)n3CCCc3c[nH]cn3)c2c1
Structure:
Search PDB for entries with ligand similarity: