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Target
Interleukin-2
Ligand
BDBM50598492
Substrate
n/a
Meas. Tech.
ChEMBL_2227131 (CHEMBL5140644)
EC50
9.4±n/a nM
Citation
 Zhu, Q; Chen, N; Tian, X; Zhou, Y; You, Q; Xu, X Hematopoietic Progenitor Kinase 1 in Tumor Immunology: A Medicinal Chemistry Perspective. J Med Chem 65:8065-8090 (2022) [PubMed] 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Human
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM50598492
Synonyms:
CHEMBL5205694
Type:
Small organic molecule
Emp. Form.:
C29H32N4O2
Mol. Mass.:
468.59
SMILES:
C[C@H]1CC(=O)c2ccc(Nc3cc4c(cnc(OC5CC5)c4cn3)[C@](C)(N)C3CC3)cc2C11CC1 |r|
Structure:
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