Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50600748
Substrate
n/a
Meas. Tech.
ChEMBL_2234756 (CHEMBL5148528)
Ki
3052±n/a nM
Citation
 Liu, S; Ding, W; Huang, W; Zhang, Z; Guo, Y; Zhang, Q; Wu, L; Li, Y; Qin, R; Li, J; Shi, T; Zhang, X; Lei, J; Hu, W Discovery of Novel Benzo[4,5]imidazo[1,2- J Med Chem 65:8933-8947 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50600748
Synonyms:
CHEMBL5176737
Type:
Small organic molecule
Emp. Form.:
C17H14N6O
Mol. Mass.:
318.3327
SMILES:
Nc1nc(cn2c1nc1ccccc21)C(=O)NCc1ccccn1
Structure:
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