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Target
Aquaporin-1
Ligand
BDBM50607939
Substrate
n/a
Meas. Tech.
ChEMBL_2271914
IC50
17500±n/a nM
Citation
 Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem 208:0 (2020) [PubMed] 
Target
Name:
Aquaporin-1
Synonyms:
AQP1 | AQP1_HUMAN | Aquaporin-1 (AQP1) | CHIP28
Type:
Protein
Mol. Mass.:
28528.18
Organism:
Human
Description:
n/a
Residue:
269
Sequence:
MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
  
Inhibitor
Name:
BDBM50607939
Synonyms:
CHEMBL1537920
Type:
Small organic molecule
Emp. Form.:
C15H12N4O2S2
Mol. Mass.:
344.411
SMILES:
S=C(NCc1ccc2OCOc2c1)Nc1ccc2nsnc2c1
Structure:
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