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Target
Transcriptional activator protein LuxR
Ligand
BDBM50527012
Substrate
n/a
Meas. Tech.
ChEMBL_2272515
IC50
600±n/a nM
Citation
 Ampomah-Wireko, M; Luo, C; Cao, Y; Wang, H; Nininahazwe, L; Wu, C Chemical probe of AHL modulators on quorum sensing in Gram-Negative Bacteria and as antiproliferative agents: A review. Eur J Med Chem 226:0 (2021) [PubMed] 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXS_ALIF1 | luxR
Type:
PROTEIN
Mol. Mass.:
28527.37
Organism:
Vibrio fischeri (strain ATCC 700601 / ES114)
Description:
ChEMBL_543884
Residue:
250
Sequence:
MNIKNINANEKIIDKIKTCNNNKDINQCLSEIAKIIHCEYYLFAIIYPHSIIKPDVSIIDNYPEKWRKYYDDAGLLEYDPVVDYSKSHHSPINWNVFEKKTIKKESPNVIKEAQESGLITGFSFPIHTASNGFGMLSFAHSDKDIYTDSLFLHASTNVPLMLPSLVDNYQKINTTRKKSDSILTKREKECLAWASEGKSTWDISKILGCSERTVTFHLTNTQMKLNTTNRCQSISKAILTGAINCPYLKN
  
Inhibitor
Name:
BDBM50527012
Synonyms:
CHEMBL4571277
Type:
Small organic molecule
Emp. Form.:
C12H12ClNO3
Mol. Mass.:
253.682
SMILES:
Clc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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