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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM50608128
Substrate
n/a
Meas. Tech.
ChEMBL_2272659
IC50
<75±n/a nM
Citation
 Van de Walle, T; Cools, L; Mangelinckx, S; D'hooghe, M Recent contributions of quinolines to antimalarial and anticancer drug discovery research. Eur J Med Chem 226:0 (2021) [PubMed] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Human
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM50608128
Synonyms:
CHEMBL5290778
Type:
Small organic molecule
Emp. Form.:
C19H15N3O2S
Mol. Mass.:
349.406
SMILES:
Cc1cc2nc(O)cc(C(=O)Nc3nc4ccccc4s3)c2cc1C
Structure:
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