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Target
Arginase-1
Ligand
BDBM50350310
Substrate
n/a
Meas. Tech.
ChEMBL_2272760
Kd
34000±n/a nM
Citation
 Xiao, YC; Yu, JL; Dai, QQ; Li, G; Li, GB Targeting Metalloenzymes by Boron-Containing Metal-Binding Pharmacophores. J Med Chem 64:17706-17727 (2021) [PubMed] 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50350310
Synonyms:
CHEMBL1812663
Type:
Small organic molecule
Emp. Form.:
C7H14BF2NO4
Mol. Mass.:
224.998
SMILES:
[NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O
Structure:
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