Reaction Details Report a problem with these data
Target
Glutathione S-transferase omega-1
Ligand
BDBM50458512
Substrate
n/a
Meas. Tech.
ChEMBL_2274061
IC50
21±n/a nM
Citation
 Deng, H; Lei, Q; Wu, Y; He, Y; Li, W Activity-based protein profiling: Recent advances in medicinal chemistry. Eur J Med Chem 191:0 (2020) [PubMed] 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM50458512
Synonyms:
CHEMBL4215608
Type:
Small organic molecule
Emp. Form.:
C21H23ClFN3O2
Mol. Mass.:
403.878
SMILES:
Fc1cccc(c1)N(C(C(=O)NC1CCCCC1)c1ccccn1)C(=O)CCl
Structure:
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