Reaction Details Report a problem with these data
Target
rRNA adenine N-6-methyltransferase
Ligand
BDBM50081279
Substrate
n/a
Meas. Tech.
ChEMBL_2299086
Ki
10000±n/a nM
Citation
 Jeremia, L; Deprez, BE; Dey, D; Conn, GL; Wuest, WM Ribosome-targeting antibiotics and resistance  RSC Med Chem 14:624-643 (2023) [PubMed] 
Target
Name:
rRNA adenine N-6-methyltransferase
Synonyms:
ERM_BACIU | Erythromycin resistance protein
Type:
PROTEIN
Mol. Mass.:
28925.75
Organism:
Bacillus subtilis
Description:
ChEMBL_67535
Residue:
244
Sequence:
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK
  
Inhibitor
Name:
BDBM50081279
Synonyms:
6-(3-Amino-phenyl)-N-indan-2-yl-[1,3,5]triazine-2,4-diamine | CHEMBL127777
Type:
Small organic molecule
Emp. Form.:
C18H18N6
Mol. Mass.:
318.3757
SMILES:
Nc1cccc(c1)-c1nc(N)nc(NC2Cc3ccccc3C2)n1
Structure:
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