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Target
DNA polymerase beta
Ligand
BDBM50615505
Substrate
n/a
Meas. Tech.
ChEMBL_2302544
IC50
5160±n/a nM
Citation
 Asakawa, Y; Ludwiczuk, A Chemical Constituents of Bryophytes: Structures and Biological Activity. J Nat Prod 81:641-660 (2018) [PubMed] 
Target
Name:
DNA polymerase beta
Synonyms:
DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB
Type:
Protein
Mol. Mass.:
38188.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
  
Inhibitor
Name:
BDBM50615505
Synonyms:
CHEMBL5290566
Type:
Small organic molecule
Emp. Form.:
C56H46O8
Mol. Mass.:
846.9596
SMILES:
Oc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2c(O)c5)cc(c4O)-c2cc-4c(CCc5ccc(Oc6cc(CCc7ccc-4c(O)c7)ccc6O)cc5)cc2O)cc3)c1
Structure:
Search PDB for entries with ligand similarity: