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Target
DNA polymerase beta
Ligand
BDBM50615499
Substrate
n/a
Meas. Tech.
ChEMBL_2302544
IC50
14400±n/a nM
Citation
 Asakawa, Y; Ludwiczuk, A Chemical Constituents of Bryophytes: Structures and Biological Activity. J Nat Prod 81:641-660 (2018) [PubMed] 
Target
Name:
DNA polymerase beta
Synonyms:
DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB
Type:
Protein
Mol. Mass.:
38188.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
  
Inhibitor
Name:
BDBM50615499
Synonyms:
MARCHANTIN B | Marchantin B
Type:
Small organic molecule
Emp. Form.:
C28H24O6
Mol. Mass.:
456.4866
SMILES:
Oc1ccc2CCc3ccc(Oc4cc(CCc5cccc(Oc2c1O)c5)cc(O)c4O)cc3
Structure:
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