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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50615958
Substrate
n/a
Meas. Tech.
ChEMBL_2304832
EC50
28±n/a nM
Citation
 Kato, T; Ohara, T; Suzuki, N; Naya, N; Fukao, K; Tokuyama, R; Muto, S; Fukasawa, H; Itai, A; Matsumura, KI Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPAR? agonists. Bioorg Med Chem 82:0 (2023) [PubMed] 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard
Type:
PROTEIN
Mol. Mass.:
49719.14
Organism:
Mus musculus
Description:
ChEMBL_1288931
Residue:
440
Sequence:
MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMGCDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKHIYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEISVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50615958
Synonyms:
CHEMBL5279586
Type:
Small organic molecule
Emp. Form.:
C23H24F3N3O2S
Mol. Mass.:
463.516
SMILES:
C[C@H]1CN(CCN1Cc1cc(C)cc(CC(O)=O)c1)c1nc2ccc(cc2s1)C(F)(F)F |r|
Structure:
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